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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
Cfx Manager 3.1 Software, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
Manager 3 1 Software, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
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Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software
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Image Search Results


Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software

Journal: Journal of molecular neuroscience : MN

Article Title: Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1 G93A ) Mouse Model of ALS

doi: 10.1007/s12031-019-01356-2

Figure Lengend Snippet: Analysis of the Klotho-induced changes in gene expression in the motor cortex (a, b) and lumbar spinal cord (c, d). The effect of Klotho overexpression in WT (a, c) and SOD1 mice (b, d) on mRNA expression of specific genes was measured using TaqMan gene expression assays (see Table 2) at 110 days (a–d) and 135 days (b, d). Bars represent fold difference (n = 6). The asterisks indicate statistical significance, *p value < 0.05 as analyzed by Bio-Rad CFX Manager 3.1 software

Article Snippet: Gene expression fold changes were determined by Bio-Rad Gene Expression Module of CFX Manager 3.1 software, and a p value ≤ 0.05 was considered significant. table ft1 table-wrap mode="anchored" t5 caption a7 Catalog number Gene expression assay Mm00446190_m1 IL-6 Mm01288386_m1 IL-10 Mm00434169_m1 IL-12a Mm00439620_m1 IL-1α Mm00434228_m1 IL-1β Mm00443258_m1 TNF-α Mm00447578_m1 Tnfaip2 Mm04208213_g1 Prdx-2 Mm00545848_m1 Prdx-3 Mm00477784_m1 NRF2 Mm01313000_m1 SOD2 Mm00440502_m1 NOS2 Mm00470018_m1 Wnt2 Mm00437330_m1 Wnt2b Mm00437347_m1 Wnt5a Mm00443610_m1 Axin2 Mm00445623_s1 Fzd5 Mm01178820_m TGF-β1 Mm00487530_m1 SMAD 2 Mm99999051_gH CCR-2 Mm00437306_m1 VEGF Mm01266402_m1 MBP Mm00487538_m1 MAG Mn01297210_m1 PLP1 Mm02619580_m1 Actin B Mm02342430_m1 PPIA Open in a separate window TaqMan gene expression assays Immunohistochemical Analysis The genders of all the mice used for IHC are listed in .

Techniques: Expressing, Over Expression, Software